Uracil factory

Uracil-ftorafur is a combination of tegafur, an oral prodrug of fluorouracil, and uracil in a 1:4 molar ratio. Tegafur is converted to fluorouracil by CYP isoenzymes and uracil prevents further degradation by competitive inhibition of dihydropyrimidine dehydrogenase. The response rate is improved by adding leucovorin. In the UK, the combination was approved by NICE for first-line treatment of metastatic colorectal cancer.

Diarrhea is a dose-limiting adverse reaction to uracil-ftorafur. However, it is less toxic than bolus fluorouracil and causes significantly less myelosuppression and mucositis. Other common adverse reactions include nausea, vomiting, fatigue, and hyperbilirubinemia. Hand–foot syndrome is very rare.

Over 30 years experience in the chemical industry, Chemwill Asia co.,Ltd is one of the leading manufacturer of Organic compounds in CHINA. One of the main products they produce is Uracil.We have extensive experience in resorcinol. At the same time, their well-trained factory and employees can ensure stable supply and fast shipments. In addition, the products have passed the CAS certification and the quality is guaranteed. Chemwill Asia co.,Ltd is your best choice for  buy resorcinol.

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